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1.

Synthesis of metal nanoparticles using Heliconia rostrata leaf extract and their antiproliferative and apoptotic property Pages 65-72 Right click to download the paper Download PDF

Authors: Lingappa Mallesha, Guruswamy Vinay, Nanjappagowda Dharmappa Rekha

DOI: 10.5267/j.ccl.2018.4.001

Keywords: Heliconia rostrate, Nanoparticles, Anti-proliferative activity

Abstract:
An ecofriendly methods for the synthesis of medicinally important class of heterocyclic scaffold, pyrazole 4-carbonitrile derivatives by one pot three component reaction of malononitrile, phenyl hydrazine and aromatic aldehyde has been achieved at room temperature. Greener protocols of reaction are followed by using sodium chloride to accelerate the reaction in aqueous media. Present methodology is a condition based divergence on synthesis of pyrazole by using simple salts, which offers several advantages like use of aqueous media and high yield of product along with short reaction time, simple work up procedure, no waste or by products, avoid the use of heavy metals or nanoparticles are the fascinating characteristics of reaction.
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Journal: CCL | Year: 2018 | Volume: 7 | Issue: 2 | Views: 1911 | Reviews: 0

 

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