Processing, Please wait...

  • Home
  • About Us
  • Search:
  • Advanced Search

Growing Science » Current Chemistry Letters » Insecticidal activity and structure activity relationship study of some synthesized hydrazone, dihydropyridine and 3-cyano-1, 4-dihydro-pyradazin-4-one derivatives against Aphis nerii

Journals

  • IJIEC (777)
  • MSL (2643)
  • DSL (690)
  • CCL (528)
  • USCM (1092)
  • ESM (421)
  • AC (562)
  • JPM (293)
  • IJDS (952)
  • JFS (101)
  • HE (32)
  • SCI (26)

CCL Volumes

    • Volume 1 (23)
      • Issue 1 (7)
      • Issue 2 (5)
      • Issue 3 (6)
      • Issue 4 (5)
    • Volume 2 (26)
      • Issue 1 (7)
      • Issue 2 (6)
      • Issue 3 (6)
      • Issue 4 (7)
    • Volume 3 (30)
      • Issue 1 (7)
      • Issue 2 (10)
      • Issue 3 (8)
      • Issue 4 (5)
    • Volume 4 (21)
      • Issue 1 (5)
      • Issue 2 (5)
      • Issue 3 (6)
      • Issue 4 (5)
    • Volume 5 (20)
      • Issue 1 (5)
      • Issue 2 (5)
      • Issue 3 (5)
      • Issue 4 (5)
    • Volume 6 (20)
      • Issue 1 (5)
      • Issue 2 (5)
      • Issue 3 (5)
      • Issue 4 (5)
    • Volume 7 (15)
      • Issue 1 (4)
      • Issue 2 (4)
      • Issue 3 (4)
      • Issue 4 (3)
    • Volume 8 (20)
      • Issue 1 (5)
      • Issue 2 (5)
      • Issue 3 (5)
      • Issue 4 (5)
    • Volume 9 (20)
      • Issue 1 (5)
      • Issue 2 (5)
      • Issue 3 (5)
      • Issue 4 (5)
    • Volume 10 (43)
      • Issue 1 (5)
      • Issue 2 (7)
      • Issue 3 (17)
      • Issue 4 (14)
    • Volume 11 (43)
      • Issue 1 (14)
      • Issue 2 (11)
      • Issue 3 (10)
      • Issue 4 (8)
    • Volume 12 (78)
      • Issue 1 (21)
      • Issue 2 (22)
      • Issue 3 (20)
      • Issue 4 (15)
    • Volume 13 (68)
      • Issue 1 (23)
      • Issue 2 (17)
      • Issue 3 (16)
      • Issue 4 (12)
    • Volume 14 (68)
      • Issue 1 (20)
      • Issue 2 (13)
      • Issue 3 (22)
      • Issue 4 (13)
    • Volume 15 (33)
      • Issue 1 (13)
      • Issue 2 (20)

Keywords

Supply chain management(168)
Jordan(165)
Vietnam(151)
Customer satisfaction(120)
Performance(115)
Supply chain(112)
Service quality(98)
Competitive advantage(97)
Tehran Stock Exchange(94)
SMEs(89)
optimization(87)
Sustainability(86)
Artificial intelligence(85)
Financial performance(84)
Trust(83)
TOPSIS(83)
Job satisfaction(81)
Genetic Algorithm(78)
Factor analysis(78)
Social media(78)


» Show all keywords

Authors

Naser Azad(82)
Zeplin Jiwa Husada Tarigan(66)
Mohammad Reza Iravani(64)
Endri Endri(45)
Muhammad Alshurideh(42)
Hotlan Siagian(40)
Dmaithan Almajali(37)
Jumadil Saputra(36)
Muhammad Turki Alshurideh(35)
Ahmad Makui(33)
Barween Al Kurdi(32)
Hassan Ghodrati(31)
Basrowi Basrowi(31)
Sautma Ronni Basana(31)
Mohammad Khodaei Valahzaghard(30)
Shankar Chakraborty(29)
Ni Nyoman Kerti Yasa(29)
Haitham M. Alzoubi(28)
Sulieman Ibraheem Shelash Al-Hawary(28)
Prasadja Ricardianto(28)


» Show all authors

Countries

Iran(2192)
Indonesia(1311)
Jordan(813)
India(793)
Vietnam(510)
Saudi Arabia(478)
Malaysia(444)
China(231)
United Arab Emirates(226)
Thailand(160)
United States(114)
Ukraine(110)
Turkey(110)
Egypt(106)
Peru(94)
Canada(93)
Morocco(86)
Pakistan(85)
United Kingdom(80)
Nigeria(78)


» Show all countries

Current Chemistry Letters

ISSN 1927-730x (Online) - ISSN 1927-7296 (Print)
Quarterly Publication
Volume 12 Issue 3 pp. 599-606 , 2023

Insecticidal activity and structure activity relationship study of some synthesized hydrazone, dihydropyridine and 3-cyano-1, 4-dihydro-pyradazin-4-one derivatives against Aphis nerii Pages 599-606 Right click to download the paper Download PDF

Authors: Mohamed S. A. El-Gaby, Modather F. Hussein, Faraghally A. Faraghally, Ali M. Drar, Mohamed A. Gad

DOI: 10.5267/j.ccl.2023.2.003

Keywords: Dihydropyridine, Pyradazin-4-one, Hydrazone, Sulfonamide, Insecticidal activity, Aphis nerii

Abstract: In our work we study the toxic effects of the prepared pyridine and pyradazine derivatives. Five compounds have been synthesized in pure state as reported procedures, and their toxicity as potential insecticidal agents against adult and nymphs of Aphis nerii were screened. The toxicity data in adults, exhibited that compound 6a is more toxic than other synthesized compounds, which LC50 was1.04 ppm while, in nymph compound 4a is more toxic than other synthesized compounds, which LC50 was 0.02 ppm. The other screened compounds showed weak to strong toxicological activity. The structure-activity relationships (SAR) for these compounds were also discussed.

How to cite this paper
El-Gaby, M., Hussein, M., Faraghally, F., Drar, A & Gad, M. (2023). Insecticidal activity and structure activity relationship study of some synthesized hydrazone, dihydropyridine and 3-cyano-1, 4-dihydro-pyradazin-4-one derivatives against Aphis nerii.Current Chemistry Letters, 12(3), 599-606.

Refrences

(1) Blackman R. L. and Eastop V. F. (2000) Aphids on the World's Crops: an Identification and Information Guide. Wiley, New York.
(2) Essig E. O. (1958) Insects and Mites of Western North America. MacMillan Publishers, New York.
(3) Hall R. W. and Ehler L. E. (1980) Population ecology of Aphis nerii on oleander. Environmental Entomology 9, 338-344.
(4) Meanwell N. A. and Seiler S. M. (1990) Drugs Future, 15, 369.
(1) Umetsu N. and Shirai Y. (2020) Development of novel pesticides in the 21st century, J. Pestic. Sci. 45 (2) 54–74.
(5) Tomizawa, M. and Casida, J. E. (2009) Molecular recognition of neonicotinoid insecticides: the determinants of life or death. Acc. Chem. Res. 42, 260−269.
(6) Tomizawa, M. (2013) Chemical biology of the nicotinic insecticide receptor. Adv. Insect Physiol. 44, 63−99.
(7) Casida, J. E. and Durkin, K. A. (2013) Neuroactive insecticides: targets, selectivity, resistance, and secondary effects. Annu. Rev. Entomol., 58, 99−117.
(8) Nauen R., Jeschke P., Velten R., Beck M. E., EbbinghausKintscher U., Thielert W.,Wölfel K., Haas M., Kunz K. and Raupach, G. (2015) Flupyradifurone: a brief profile of a new butenolide insecticide. Pest Manage. Sci., 71, 850−862.
(9) Cordova D., Benner E. A., Schroeder M. E., Holyoke C. W., Zhang W., Pahutski T. F., Leighty R. M., Vincent, D. R. and Hamm, J. C. (2016) Mode of action of triflumezopyrim: a novel mesoionic insecticide which inhibits the nicotinic acetylcholine receptor. Insect Biochem. Mol. Biol. 74, 32−41.
(10) Pahutski T. F. (2012) Mesoionic pyrido[1,2-a]pyrimidine pesticides. PCT Int. Appl. WO 2012092115 A1.
(11) Zhang W., Holyoke C. W., Jr.; Barry J., Cordova D., Leighty R. M., Tong M.-H. T., Hughes K. A., Lahm G. P., Pahutski T. F., Xu M., Briddell T. A., McCann S. F., Henry Y. T.and Chen Y. (2017) Mesoionic pyrido[1,2a]pyrimidinones: Discovery of dicloromezotiaz as a lepidoptera insecticide acting on the nicotinic acetylcholine receptors. Bioorg. Med. Chem. Lett. 27, 911−917
(12) Kagabu, S.; Mitomi, M.; Kitsuda, S.; Horikoshi, R.; Nomura, M. and Onozaki, Y. (2013) Pest control agent. US 9073866B2.
(13) AbdelhamidA. A., Aref S. A., Ahmed N. A., Elsaghier A. M. M, Abd El Latif F. M., Al-Ghamdi S. N., and Gad M. A. (2023) Design, Synthesis, and Toxicological Activities of Novel Insect Growth Regulators as Insecticidal Agents against Spodoptera littoralis (Boisd). ACS Omega. 8 (1) 709-717.
(14) El-Dean A. M. K., Abd-Ella A. A., Hassanien R., El-Sayed M. E., and Abdel-Raheem S. A. A. (2019) Design, Synthesis, Characterization, and Insecticidal Bioefficacy Screening of Some New Pyridine Derivatives.ACS Omega. 4 (2019) 8406–8412.
(15) Hedrich L. W., Patel N. R., and Kirkpatrick J. L. (1982) Heterocyclic-Substituted Hydrazides and Hydrazones as Plant Growth Regulators. US patent US4, 319, 026A.
(16) Wang Y., Yu X., Zhi X., Xiao X., Yang C., and Xu H. (2014) Synthesis and insecticidal activity of novel hydrazone compounds derived from a naturally occurring lignan podophyllotoxin against Mythimnaseparata (Walker). Bioorganic & Medicinal Chemistry Letters. 24 (12) 2621–4.
(18) Kula K., Łapczuk A., Sadowski M., Kras J., Zawadzińska K., Demchuk O. M., Gaurav G. K., Wróblewska A., Jasiński R. (2022) On the Question of the Formation of Nitro-Functionalized 2,4-Pyrazole Analogs on the Basis of Nitrylimine Molecular Systems and 3,3,3-Trichloro-1-Nitroprop-1-Ene. Molecules. 27(23), 8409-8424.
(19) Fryźlewicz A., Olszewska A., Zawadzińska K., Woliński P., Kula K., Kącka-Zych A,, Łapczuk-Krygier A. and Jasiński R. (2022) On the Mechanism of the Synthesis of Nitrofunctionalised Δ2-Pyrazolines via [3+2] Cycloaddition Reactions between α-EWG-Activated Nitroethenes and Nitrylimine TAC Systems. Organics. 3 (1) 59-76.
(20) Kula K., Kącka-Zych A., Łapczuk-Krygier A., Wzorek Z., Nowak A. K. and Jasiński R. (2021) Experimental and Theoretical Mechanistic Study on the Thermal Decomposition of 3,3-diphenyl-4-(trichloromethyl)-5-nitropyrazoline. Molecules. 26 (5) 1364-1389.
(21) Fryźlewicz A., Łapczuk-Krygier A., Kula K., Demchuk O. M., Dresler E. and Jasiński R. (2021) Regio- and stereoselective synthesis of nitrofunctionalized 1,2-oxazolidine analogs of nicotine Chem. Heterocycl. Compd., 56 (1) 120-122.
(22) Kula K., Joanna Dobosz J., Jasinski R., Kacka-Zych A., Łapczuk-Krygier A., Mirosław B., and Demchuk O. M. (2020) [3+2] Cycloaddition of diaryldiazomethanes with (E)-3,3,3-trichloro-1-nitroprop-1-ene: An experimental, theoretical and structural study. J. Mol. Struct. 1203 (2020) 127473-12783.
(23) Aggarwal N., Kumar R., Srivastva C., Dureja P., and Khurana J. M. (2010) Synthesis of Nalidixic Acid Based Hydrazones as Novel Pesticides. J Agric Food Chem.58 (5) 3056–61.
(24) Liu G., Zhou C., Zhang Z., Wang C., Luo X., Ju X., Zhao C. and Ozoe Y.(2022) Novel insecticidal 1,6-dihydro-6-iminopyridazine derivatives as competitive antagonists of insect RDL GABA receptors. Pest Manag Sci. 78, 2872–2882.
(25) El-Gaby M. S. A. (2004) Syntheses of Hitherto Unknown Thiazole, Ylidene and Pyridinethione Derivatives Having a Piperidin-1-yl Moiety and Their Use as Antimicrobial Agents , J. the Chinese Chemical Society, 51, 125-134.
(26) El-Gaby M. S. A. (2003) Synthesis and antimicrobial evaluation of some newly 4-sulfamoyl phenylhydrazone,azopyrazole,azopyrazolo[1,5-a]pyrimidine, dihydro pyradazine and pyradazin-4-one, Al-Azhar Bull. Sci., 14, 417-428.
(27) Abdelhamid A. A., Elsaghier A. M. M., Aref S. A., Gad M. A., Ahmed N. A., and Abdel-Raheem Sh. A. A. (2021) Preparation and biological activity evaluation of some benzoylthiourea and benzoylurea compounds. Curr. Chem. Lett., 10 (4) 371-376.
(28) Gad M. A., Aref S. A., Abdelhamid A. A., Elwassimy M. M., and Abdel-Raheem Sh. A. A. (2021) Biologically active organic compounds as insect growth regulators (IGRs): introduction, mode of action, and some synthetic methods. Curr. Chem. Lett., 10 (4) 393-412.
(29) Abdelhamid A. A., Elwassimy M. M., Aref S. A., and Gad M. A. (2019) Chemical design and bioefficacy screening of new insect growth regulators as potential insecticidal agents against Spodoptera littoralis (Boisd.). Biotechnology Reports, 24 (2019) 394-401.
(30) Abdelhamid A. A, Salama K. S. M., Elsayed A. M., Gad M. A., and El-Remaily M. A. A. A. (2022) Synthesis and Toxicological effect of some new pyrrole derivatives as prospective insecticidal agents against the cotton leafworm, spodoptera littoralis (Boisduval). ACS Omega, 7 (2022) 3990-4000.
(31) El-Gaby M. S. A., Ammar Y. A., Drar A. M., Gad M. A. (2022) Insecticidal bioefficacy screening of some chalcone and acetophenone hydrazone derivatives on Spodopetra Frugiperda (Lepidoptera: Noctuidae). Curr. Chem. Lett., 11 (4) 263-268.
(32) Jasinski J. P., Akkurt M., Mohamed Sh. K., Gad M. A. and Albayati M. R. (2015) Crystal structure of N-(propan-2-yl-carbamothioyl)benzamide. Acta Cryst., 71 (1) 56-57.
(33) Bakhite E. A., Marae I. S., Gad M. A., Mohamed Sh. K., Mague J. T., and Abuelhassan S. (2022) Pyridine Derivatives as Insecticides. Part 3. Synthesis, Crystal Structure, and Toxicological Evaluation of Some New Partially Hydrogenated Isoquinolines against Aphis gossypii (Glover, 1887). J. Agric. Food Chem. 70 (31) 9637–9644.
(34) Ali M. A., Salah H., Gad M. A., Youssef M. A. M, and Elkanzi N. A. A. (2022) Design, Synthesis, and SAR Studies of Some Novel Chalcone Derivatives for Potential Insecticidal Bioefficacy Screening on Spodoptera frugiperda (Lepidoptera: Noctuidae). ACS Omega. 7 (44) 40091-40097.
(35) Khodairy A.,Mansour, Erian. S., Elhady, Omar M., Drar, A. M. (2021) Novel N-cyanoguanidyl derivatives: Synthesis and studying their toxicological activity against Spodoptera littoralis and schizaphisgraminum. Curr. Chem. Lett. 10 (4) 363 – 370.
(36) Khodairy A., Mansour, Erian. S., Elhady, Omar M., Drar, A. M. (2021) Synthesis of Neonicotinoid analogues and study their toxicological aspects on Spodoptera littoralis and Schizaphis graminum. Int. J Pest Manag., Accepted Manuscript (DOI: 10.1080/09670874.2021.1943048)..
(37) Abbott W. S. (1925) A method of computing the effectiveness of an insecticide. J. Econ. Entomol., 18 (2) 265-267.
(38) Finny D. J. (1952) Probit analysis: A statistical treatment of the sigmoid response curve, 2nd Ed, Cambridge Univ. Press, Cambridge, U. K.
  • 0
  • 1
  • 2
  • 3
  • 4
  • 5

Journal: Current Chemistry Letters | Year: 2023 | Volume: 12 | Issue: 3 | Views: 1039 | Reviews: 0

Related Articles:
  • Insecticidal efficacy and structure activity relationship study of some syn ...
  • Toxicity assessment of certain insecticides on the red soft scale insect, P ...
  • Insecticidal bioefficacy screening of some chalcone and acetophenone hydraz ...
  • Synthesis and characterization of some new tebufenozide analogues and study ...
  • Synthesis and spectral characterization of selective pyridine compounds as ...

Add Reviews

Name:*
E-Mail:
Review:
Bold Italic Underline Strike | Align left Center Align right | Insert smilies Insert link URLInsert protected URL Select color | Add Hidden Text Insert Quote Convert selected text from selection to Cyrillic (Russian) alphabet Insert spoiler
winkwinkedsmileam
belayfeelfellowlaughing
lollovenorecourse
requestsadtonguewassat
cryingwhatbullyangry
Security Code: *
Include security image CAPCHA.
Refresh Code

® 2010-2026 GrowingScience.Com