How to cite this paper
Abdel-Raheem, S., El-Dean, A., ul-Malik, M., Hassanien, R., El-Sayed, M., Abd-Ella, A., Zawam, S & Tolba, M. (2022). Synthesis of new distyrylpyridine analogues bearing amide substructure as effective insecticidal agents.Current Chemistry Letters, 11(1), 23-28.
Refrences
(1) Guan A., Liu C., Yang X., and Dekeyser M. (2014) Application of the intermediate derivatization approach in agrochemical discovery. Chem. Rev., 114 (14) 7079-7107.
(2) Popp J., Pető K., and Nagy J. (2013) Pesticide productivity and food security. A review. Agron. Sustain. Dev., 33 (1) 243-255.
(3) Su W., Zhou Y., Ma Y., Wang L., Zhang Z., Rui C., and Qin Z. (2012) N′-Nitro-2-hydrocarbylidenehydrazinecarboximidamides: design, synthesis, crystal structure, insecticidal activity, and structure–activity relationships. J. Agric. Food Chem., 60 (20) 5028-5034.
(4) Zhang Y., Lorsbach B. A., Castetter S., Lambert W. T., Kister J., Wang N. X., and Loso M. R. (2018) Physicochemical property guidelines for modern agrochemicals. Pest Manag. Sci., 74 (9) 1979-1991.
(5) Lamberth C. (2013) Heterocyclic chemistry in crop protection. Pest Manag. Sci., 69 (10) 1106-1114.
(6) Xu F., Wang Y., Luo D., Yu G., Wu Y., Dai A., and Wu J. (2018) Novel Trifluoromethyl Pyridine Derivatives Bearing a 1,3,4‐Oxadiazole Moiety as Potential Insecticide. ChemistrySelect, 3 (10) 2795-2799.
(7) Wang Y., Xu F., Yu G., Shi J., Li C., Liu Z., and Wu J. (2017) Synthesis and insecticidal activity of diacylhydrazine derivatives containing a 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole scaffold. Chem. Cent. J., 11 (1) 1-11.
(8) Xu F. Z., Wang Y. Y., Luo D. X., Yu G., Guo S. X., Fu H., and Wu J. (2018) Design, synthesis, insecticidal activity and 3D-QSR study for novel trifluoromethyl pyridine derivatives containing an 1,3,4-oxadiazole moiety. RSC Adv., 8 (12) 6306-6314.
(9) Yang S., Tian X. Y., Ma T. Y., Dai L., Ren C. L., Mei J. C., and Tan C. X. (2020) Synthesis and biological activity of benzamides substituted with pyridine-linked 1,2,4-oxadiazole. Molecules, 25 (15) 3500.
(10) Jeschke P. (2010) The unique role of halogen substituents in the design of modern agrochemicals. Pest Manag. Sci., 66 (1) 10-27.
(11) Khodairy A., Mansour E. S., Elhady O. M., and Drar A. M. (2021) Novel N-cyanoguanidyl derivatives: Synthesis and studying their toxicological activity against Spodoptera littoralis and Schizaphis graminum. Curr. Chem. Lett., 10 (4) 363-370.
(12) Elhady O. M., Mansour E. S., Elwassimy M. M., Zawam S. A., and Drar A. M. (2021) Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.). Curr. Chem. Lett., Accepted Manuscript (DOI: 10.5267/j.ccl.2021.9.005).
(13) Khodairy A., Mansour E. S., Elhady O. M., and Drar A. M. (2021) Synthesis of Neonicotinoid analogues and study their toxicological aspects on Spodoptera littoralis and Schizaphis graminum. Int. J. Pest Manag., Accepted Manuscript (DOI: 10.1080/09670874.2021.1943048).
(14) Abdel-Raheem Sh. A. A., Kamal El-Dean A. M., Hassanien R., El-Sayed M. E. A., and Abd-Ella A. A. (2020) Synthesis and biological activity of 2-((3-Cyano-4,6-distyrylpyridin-2-yl)thio)acetamide and its cyclized form. Alger. j. biosciences, 01 (02) 046-050.
(15) Bakhite E. A., Abd-Ella A. A., El-Sayed M. E. A., and Abdel-Raheem Sh. A. A. (2014) Pyridine derivatives as insecticides. Part 1: Synthesis and toxicity of some pyridine derivatives against Cowpea Aphid, Aphis craccivora Koch (Homoptera: Aphididae). J. Agric. Food Chem., 62 (41) 9982–9986.
(16) Abdelhamid A. A., Elsaghier A. M. M., Aref S. A., Gad M. A., Ahmed N. A., and Abdel-Raheem Sh. A. A. (2021) Preparation and biological activity evaluation of some benzoylthiourea and benzoylurea compounds. Curr. Chem. Lett., 10 (4) 371-376.
(17) Bakhite E. A., Abd-Ella A. A., El-Sayed M. E. A., and Abdel-Raheem Sh. A. A. (2017) Pyridine derivatives as insecticides. Part 2: Synthesis of some piperidinium and morpholinium cyanopyridinethiolates and their Insecticidal Activity. J. Saud. Chem. Soc., 21 (1) 95–104.
(18) Kamal El-Dean A. M., Abd-Ella A. A., Hassanien R., El-Sayed M. E. A., Zaki R. M., and Abdel-Raheem Sh. A. A. (2019) Chemical design and toxicity evaluation of new pyrimidothienotetrahydroisoquinolines as potential insecticidal agents. Toxicol. Rep., 6 (2019) 100-104.
(19) Gad M. A., Aref S. A., Abdelhamid A. A., Elwassimy M. M., and Abdel-Raheem Sh. A. A. (2021) Biologically active organic compounds as insect growth regulators (IGRs): introduction, mode of action, and some synthetic methods. Curr. Chem. Lett., 10 (4) 393-412.
(20) Kamal El-Dean A. M., Abd-Ella A. A., Hassanien R., El-Sayed M. E. A., and Abdel-Raheem Sh. A. A. (2019) Design, Synthesis, Characterization, and Insecticidal Bioefficacy Screening of Some New Pyridine Derivatives. ACS Omega, 4 (5) 8406-8412.
(21) Abdel-Raheem Sh. A. A., Kamal El-Dean A. M., Zaki R. M., Hassanien R., El-Sayed M. E. A., Sayed M., and Abd-Ella A. A. (2021) Synthesis and toxicological studies on distyryl-substituted heterocyclic insecticides. Eur. Chem. Bull., 10 (4) 225-229.
(22) Abdel-Raheem Sh. A. A., Kamal El-Dean A. M., Hassanien R., El-Sayed M. E. A., and Abd-Ella A. A. (2021) Synthesis and characterization of some distyryl-derivatives for agricultural uses. Eur. Chem. Bull., 10 (1) 35-38.
(23) Tolba M. S., Sayed M., Abdel-Raheem Sh. A. A., Gaber T. A., Kamal El-Dean A. M., and Ahmed M. (2021) Synthesis and spectral characterization of some new thiazolopyrimidine derivatives. Curr. Chem. Lett., 10 (4) 471-478.
(24) Al-Taifi E. A., Abdel-Raheem Sh. A. A., and Bakhite E. A. (2016) Some reactions of 3-cyano-4-(p-methoxyphenyl)-5-oxo-5,6,7,8-tetrahydroquinoline-2(1H)-thione; Synthesis of new tetrahydroquinolines and tetrahydrothieno[2,3-b]quinolines. Assiut University Journal of Chemistry (AUJC), 45 (1) 24-32.
(25) Abdel-Raheem Sh. A. A., Kamal El-Dean A. M., Hassanien R., El-Sayed M. E. A., Sayed M., and Abd-Ella A. A. (2021) Synthesis and spectral characterization of selective pyridine compounds as
bioactive agents. Curr. Chem. Lett., 10 (3) 255-260.
(26) Abdel-Raheem Sh. A. A., Kamal El-Dean A. M., Abd ul-Malik M. A., Abd-Ella A. A., Al-Taifi E. A., Hassanien R., El-Sayed M. E. A., Mohamed S. K., Zawam S. A., and Bakhite E. A. (2021) A concise review on some synthetic routes and applications of pyridine scaffold compounds. Curr. Chem. Lett., 10 (4) 337-362.
(27) Tolba M. S., Kamal El-Dean A. M., Ahmed M., Hassanien R., Sayed M., Zaki R. M., Mohamed S. K., Zawam S. A., and Abdel-Raheem Sh. A. A. (2021) Synthesis, reactions, and applications of pyrimidine derivatives. Curr. Chem. Lett., Accepted Manuscript (DOI: 10.5267/j.ccl.2021.8.002).
(28) Abdelhafeez I. A., El-Tohamy S. A., Abd ul-Malik M. A., Abdel-Raheem Sh. A. A., and El-Dars F. M. S. (2021) A review on green remediation techniques for hydrocarbons and heavy metals contaminated soil. Curr. Chem. Lett., Accepted Manuscript (DOI: 10.5267/j.ccl.2021.9.006).
(29) Tolba M. S., Abd ul-Malik M. A., Kamal El-Dean A. M., Geies A. A., Radwan Sh. M., Zaki R. M., Sayed M., Mohamed S. K., and Abdel-Raheem Sh. A. A. (2021) An overview on synthesis and reactions of coumarin based compounds. Curr. Chem. Lett., Accepted Manuscript (10.5267/j.ccl.2021.9.007).
(30) Saber A. F., Sayed M., Tolba M. S., Kamal A. M., Hassanien R., and Ahmed M. (2021) A Facile Method for Preparation and Evaluation of the Antimicrobial Efficiency of Various Heterocycles Containing Thieno[2,3-d]Pyrimidine. Synth. Commun, 51 (3) 398-409.
(31) Ahmed M., Sayed M., Saber A. F., Hassanien R., Kamal El-Dean A. M., and Tolba M. S. (2020) Synthesis, Characterization, and Antimicrobial Activity of New Thienopyrimidine Derivatives. Polycycl. Aromat. Compd., Accepted Manuscript (DOI: 10.1080/10406638.2020.1852587).
(32) Kamal El-Dean A. M., Zaki R. M., Radwan S. M., and Saber A. F. (2017) Synthesis, Reactions and Spectral Characterization of Novel Thienopyrazole Derivatives. Eur. Chem. Bull., 6 (12) 550–553.
(33) Zaki R. M., Kamal El-Dean A. M., Radwan S. M., and Saber A. F. (2019) Efficient synthesis, reactions and spectral characterization of novel pyrazolo[4’,3’:4,5]thieno[3,2-d]pyrimidine derivatives and their related heterocycles. Heterocycl. Commun., 25 (1) 39–46.
(34) Saber A. F., Zaki R. M., Kamal El-Dean A. M., and Radwan S. M. (2020) Synthesis, reactions and spectral characterization of some new biologically active compounds derived from thieno[2,3-c]pyrazole-5-carboxamide. J. Heterocyclic Chem., 57 (1) 238–247.
(35) Sayed M., Kamal El-Dean A. M., Ahmed M., and Hassanien R. (2017) Synthesis of some new heterocyclic compounds containing indole moiety. Eur. Chem. Bull., 6 (4) 171-176.
(36) Sayed M., Kamal El-Dean A. M., Ahmed M., and Hassanien R. (2018) Synthesis of Some Heterocyclic Compounds Derived from Indole as Antimicrobial Agents. Synth. Commun., 48 (4) 413–421.
(37) Sayed M., Younis O., Hassanien R., Ahmed M., Mohammed A. A. K., Kamal A. M., and Tsutsumi O. (2019) Design and synthesis of novel indole derivatives with aggregation-induced emission and antimicrobial Activity. J. Photochem. Photobiol. A., 383 (2019) 111969–111979.
(38) Kamal El Dean A. M., Zaki R. M., Geies A. A., Radwan S. M., and Tolba M. S. (2013) Synthesis and Antimicrobial Activity of New Heterocyclic Compounds Containing Thieno[3,2-c]Coumarin and Pyrazolo[4,3-c]Coumarin Frameworks. Russ. J. Bioorganic Chem., 39 (5) 553–564.
(39) Ahmed M., Younis O., Orabi E. A., Sayed A. M., Kamal El-Dean A. M., Hassanien R., Davis R. L., Tsutsumi O., and Tolba M. S. (2020) Synthesis of novel thienopyrimidines as biocompatible chromophores with aggregation-induced emission sensitive to molecular aggregation. ACS Omega, 5 (46) 29988-30000.
(40) Tolba M. S., Kamal El-Dean A. M., Ahmed M., Hassanien R., and Farouk M. (2017) Synthesis and Antimicrobial Activity of Some New Thienopyrimidine Derivatives. Arkivoc, 2017 (5) 229–243.
(41) Tolba M. S., Ahmed M., Kamal El-Dean A. M., Hassanien R., and Farouk M. (2018) Synthesis of new fused thienopyrimidines derivatives as anti-inflammatory agents. J. Heterocyclic Chem., 55 (2) 408–418.
(42) Younis O., Tolba M. S., Orabi E. A., Kamal A. M., Hassanien R., Tsutsumi O., and Ahmed M. (2020) Biologically-active heterocyclic molecules with aggregation-induced blue-shifted emission and efficient luminescence both in solution and solid states. J. Photochem. Photobiol. A., 400 (2020) 112642-112653.
(43) Tolba M. S., Kamal El-Dean A. M., Ahmed M., and Hassanien R. (2019) Synthesis, reactions, and biological study of some new thienopyrimidine derivatives as antimicrobial and antiInflammatory agents. J. Chin. Chem. Soc., 66 (5) 548–557.
(44) Hamed M. M., Kamal El-Dean A. M., Abdel-Mohsen Sh. A., and Tolba M. S. (2021) New Diclofenac Derivatives as Anti-Microbial, Anti-Inflammatory Agents: Design, Synthesis, Biological Screening, and Molecular Docking Study. Russ. J. Bioorganic Chem., 47 (1) 208-220.
(45) Abeed A. A. O., and Abdel Mohsen Sh. A. (2013) Synthesis, characterization and antimicrobial activity of new thiadiazoles, thiazolidines, and spiro (indole-azoles) linked to 2-pyrazolin-5-one. Eur. J. Sci. Res., 108 (2) 279-285.
(46) Bakhite E. A., Abeed A. A. O., and Ola E. A. Ahmed (2016) Synthesis and biological activity of some new fused thieno[2,3-b]pyridine derivatives; pyridothienopyrimidinones and pyridothienotriazinones. Assiut University Journal of Chemistry (AUJC), 45 (1) 47-57.
(47) Youssef M. S. K., Abeed A. A. O., and El Emary T. I. (2017) Synthesis and evaluation of chromene-based compounds containing pyrazole moiety as antimicrobial agents. Heterocycl commun., 23 (1) 55-64.
(48) Abeed A. A. O., Youssef M. S. K., and Rehab Hegazy R. (2017) Synthesis, anti-diabetic and renoprotective activity of some new benzazole, thiazolidin-4-one and azetidin-2-one derivatives. J. Braz. Chem. Soc., 28 (11) 2054-2063.
(49) Bakhite E. A., Abeed A. A. O., and Ahmed O. A. (2017) Fused thieno[2,3-b]pyridines: synthesis and characterization of new condensed pyridothienopyrimidines. Arkivoc, 2017 (4) 121-136.
(50) Youssef M. S. K., and Omar A. A. (2007) Synthesis and reactions of 5-amino-3-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-7-phenyl-7H-thiazolo[3,2-a]pyrimidine-6-carbonitrile. Monatsh. Chem., 138 (10) 989-995.
(51) Youssef M. S. K., Abbady M. S. A., Ahmed R. A., and Omar A. A. (2008) Reactions of 4-(2-aminothiazole-4-yl)-3-methyl-5-oxo-1-phenyl-2-pyrazo-line. Synthesis of thiazolo[3,2-a]pyrimidine and imidazo[2,1-b]thiazole derivatives. Monatsh. Chem., 139 (5) 553-559.
(52) O’Brien P. J., Abdel-Aal Y. A., Ottea J. A., and Graves J. B. (1992) Relationship of insecticide resistance to carboxylesterases in Aphis gossypii (Homoptera: Aphididae) from Midsouth cotton. J. Econ. Entomol., 85 651–657.
(53) Abbott W. S. (1925) A method of computing the effectiveness of an insecticide. J. Econ. Entomol., 18 265–267.
(54) Finney D. J. (1952) Probit Analysis: A Statistical Treatment of the Sigmoid Response Curve, 2nd Ed, Cambridge Univ. Press, Cambridge, U. K.
(2) Popp J., Pető K., and Nagy J. (2013) Pesticide productivity and food security. A review. Agron. Sustain. Dev., 33 (1) 243-255.
(3) Su W., Zhou Y., Ma Y., Wang L., Zhang Z., Rui C., and Qin Z. (2012) N′-Nitro-2-hydrocarbylidenehydrazinecarboximidamides: design, synthesis, crystal structure, insecticidal activity, and structure–activity relationships. J. Agric. Food Chem., 60 (20) 5028-5034.
(4) Zhang Y., Lorsbach B. A., Castetter S., Lambert W. T., Kister J., Wang N. X., and Loso M. R. (2018) Physicochemical property guidelines for modern agrochemicals. Pest Manag. Sci., 74 (9) 1979-1991.
(5) Lamberth C. (2013) Heterocyclic chemistry in crop protection. Pest Manag. Sci., 69 (10) 1106-1114.
(6) Xu F., Wang Y., Luo D., Yu G., Wu Y., Dai A., and Wu J. (2018) Novel Trifluoromethyl Pyridine Derivatives Bearing a 1,3,4‐Oxadiazole Moiety as Potential Insecticide. ChemistrySelect, 3 (10) 2795-2799.
(7) Wang Y., Xu F., Yu G., Shi J., Li C., Liu Z., and Wu J. (2017) Synthesis and insecticidal activity of diacylhydrazine derivatives containing a 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole scaffold. Chem. Cent. J., 11 (1) 1-11.
(8) Xu F. Z., Wang Y. Y., Luo D. X., Yu G., Guo S. X., Fu H., and Wu J. (2018) Design, synthesis, insecticidal activity and 3D-QSR study for novel trifluoromethyl pyridine derivatives containing an 1,3,4-oxadiazole moiety. RSC Adv., 8 (12) 6306-6314.
(9) Yang S., Tian X. Y., Ma T. Y., Dai L., Ren C. L., Mei J. C., and Tan C. X. (2020) Synthesis and biological activity of benzamides substituted with pyridine-linked 1,2,4-oxadiazole. Molecules, 25 (15) 3500.
(10) Jeschke P. (2010) The unique role of halogen substituents in the design of modern agrochemicals. Pest Manag. Sci., 66 (1) 10-27.
(11) Khodairy A., Mansour E. S., Elhady O. M., and Drar A. M. (2021) Novel N-cyanoguanidyl derivatives: Synthesis and studying their toxicological activity against Spodoptera littoralis and Schizaphis graminum. Curr. Chem. Lett., 10 (4) 363-370.
(12) Elhady O. M., Mansour E. S., Elwassimy M. M., Zawam S. A., and Drar A. M. (2021) Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.). Curr. Chem. Lett., Accepted Manuscript (DOI: 10.5267/j.ccl.2021.9.005).
(13) Khodairy A., Mansour E. S., Elhady O. M., and Drar A. M. (2021) Synthesis of Neonicotinoid analogues and study their toxicological aspects on Spodoptera littoralis and Schizaphis graminum. Int. J. Pest Manag., Accepted Manuscript (DOI: 10.1080/09670874.2021.1943048).
(14) Abdel-Raheem Sh. A. A., Kamal El-Dean A. M., Hassanien R., El-Sayed M. E. A., and Abd-Ella A. A. (2020) Synthesis and biological activity of 2-((3-Cyano-4,6-distyrylpyridin-2-yl)thio)acetamide and its cyclized form. Alger. j. biosciences, 01 (02) 046-050.
(15) Bakhite E. A., Abd-Ella A. A., El-Sayed M. E. A., and Abdel-Raheem Sh. A. A. (2014) Pyridine derivatives as insecticides. Part 1: Synthesis and toxicity of some pyridine derivatives against Cowpea Aphid, Aphis craccivora Koch (Homoptera: Aphididae). J. Agric. Food Chem., 62 (41) 9982–9986.
(16) Abdelhamid A. A., Elsaghier A. M. M., Aref S. A., Gad M. A., Ahmed N. A., and Abdel-Raheem Sh. A. A. (2021) Preparation and biological activity evaluation of some benzoylthiourea and benzoylurea compounds. Curr. Chem. Lett., 10 (4) 371-376.
(17) Bakhite E. A., Abd-Ella A. A., El-Sayed M. E. A., and Abdel-Raheem Sh. A. A. (2017) Pyridine derivatives as insecticides. Part 2: Synthesis of some piperidinium and morpholinium cyanopyridinethiolates and their Insecticidal Activity. J. Saud. Chem. Soc., 21 (1) 95–104.
(18) Kamal El-Dean A. M., Abd-Ella A. A., Hassanien R., El-Sayed M. E. A., Zaki R. M., and Abdel-Raheem Sh. A. A. (2019) Chemical design and toxicity evaluation of new pyrimidothienotetrahydroisoquinolines as potential insecticidal agents. Toxicol. Rep., 6 (2019) 100-104.
(19) Gad M. A., Aref S. A., Abdelhamid A. A., Elwassimy M. M., and Abdel-Raheem Sh. A. A. (2021) Biologically active organic compounds as insect growth regulators (IGRs): introduction, mode of action, and some synthetic methods. Curr. Chem. Lett., 10 (4) 393-412.
(20) Kamal El-Dean A. M., Abd-Ella A. A., Hassanien R., El-Sayed M. E. A., and Abdel-Raheem Sh. A. A. (2019) Design, Synthesis, Characterization, and Insecticidal Bioefficacy Screening of Some New Pyridine Derivatives. ACS Omega, 4 (5) 8406-8412.
(21) Abdel-Raheem Sh. A. A., Kamal El-Dean A. M., Zaki R. M., Hassanien R., El-Sayed M. E. A., Sayed M., and Abd-Ella A. A. (2021) Synthesis and toxicological studies on distyryl-substituted heterocyclic insecticides. Eur. Chem. Bull., 10 (4) 225-229.
(22) Abdel-Raheem Sh. A. A., Kamal El-Dean A. M., Hassanien R., El-Sayed M. E. A., and Abd-Ella A. A. (2021) Synthesis and characterization of some distyryl-derivatives for agricultural uses. Eur. Chem. Bull., 10 (1) 35-38.
(23) Tolba M. S., Sayed M., Abdel-Raheem Sh. A. A., Gaber T. A., Kamal El-Dean A. M., and Ahmed M. (2021) Synthesis and spectral characterization of some new thiazolopyrimidine derivatives. Curr. Chem. Lett., 10 (4) 471-478.
(24) Al-Taifi E. A., Abdel-Raheem Sh. A. A., and Bakhite E. A. (2016) Some reactions of 3-cyano-4-(p-methoxyphenyl)-5-oxo-5,6,7,8-tetrahydroquinoline-2(1H)-thione; Synthesis of new tetrahydroquinolines and tetrahydrothieno[2,3-b]quinolines. Assiut University Journal of Chemistry (AUJC), 45 (1) 24-32.
(25) Abdel-Raheem Sh. A. A., Kamal El-Dean A. M., Hassanien R., El-Sayed M. E. A., Sayed M., and Abd-Ella A. A. (2021) Synthesis and spectral characterization of selective pyridine compounds as
bioactive agents. Curr. Chem. Lett., 10 (3) 255-260.
(26) Abdel-Raheem Sh. A. A., Kamal El-Dean A. M., Abd ul-Malik M. A., Abd-Ella A. A., Al-Taifi E. A., Hassanien R., El-Sayed M. E. A., Mohamed S. K., Zawam S. A., and Bakhite E. A. (2021) A concise review on some synthetic routes and applications of pyridine scaffold compounds. Curr. Chem. Lett., 10 (4) 337-362.
(27) Tolba M. S., Kamal El-Dean A. M., Ahmed M., Hassanien R., Sayed M., Zaki R. M., Mohamed S. K., Zawam S. A., and Abdel-Raheem Sh. A. A. (2021) Synthesis, reactions, and applications of pyrimidine derivatives. Curr. Chem. Lett., Accepted Manuscript (DOI: 10.5267/j.ccl.2021.8.002).
(28) Abdelhafeez I. A., El-Tohamy S. A., Abd ul-Malik M. A., Abdel-Raheem Sh. A. A., and El-Dars F. M. S. (2021) A review on green remediation techniques for hydrocarbons and heavy metals contaminated soil. Curr. Chem. Lett., Accepted Manuscript (DOI: 10.5267/j.ccl.2021.9.006).
(29) Tolba M. S., Abd ul-Malik M. A., Kamal El-Dean A. M., Geies A. A., Radwan Sh. M., Zaki R. M., Sayed M., Mohamed S. K., and Abdel-Raheem Sh. A. A. (2021) An overview on synthesis and reactions of coumarin based compounds. Curr. Chem. Lett., Accepted Manuscript (10.5267/j.ccl.2021.9.007).
(30) Saber A. F., Sayed M., Tolba M. S., Kamal A. M., Hassanien R., and Ahmed M. (2021) A Facile Method for Preparation and Evaluation of the Antimicrobial Efficiency of Various Heterocycles Containing Thieno[2,3-d]Pyrimidine. Synth. Commun, 51 (3) 398-409.
(31) Ahmed M., Sayed M., Saber A. F., Hassanien R., Kamal El-Dean A. M., and Tolba M. S. (2020) Synthesis, Characterization, and Antimicrobial Activity of New Thienopyrimidine Derivatives. Polycycl. Aromat. Compd., Accepted Manuscript (DOI: 10.1080/10406638.2020.1852587).
(32) Kamal El-Dean A. M., Zaki R. M., Radwan S. M., and Saber A. F. (2017) Synthesis, Reactions and Spectral Characterization of Novel Thienopyrazole Derivatives. Eur. Chem. Bull., 6 (12) 550–553.
(33) Zaki R. M., Kamal El-Dean A. M., Radwan S. M., and Saber A. F. (2019) Efficient synthesis, reactions and spectral characterization of novel pyrazolo[4’,3’:4,5]thieno[3,2-d]pyrimidine derivatives and their related heterocycles. Heterocycl. Commun., 25 (1) 39–46.
(34) Saber A. F., Zaki R. M., Kamal El-Dean A. M., and Radwan S. M. (2020) Synthesis, reactions and spectral characterization of some new biologically active compounds derived from thieno[2,3-c]pyrazole-5-carboxamide. J. Heterocyclic Chem., 57 (1) 238–247.
(35) Sayed M., Kamal El-Dean A. M., Ahmed M., and Hassanien R. (2017) Synthesis of some new heterocyclic compounds containing indole moiety. Eur. Chem. Bull., 6 (4) 171-176.
(36) Sayed M., Kamal El-Dean A. M., Ahmed M., and Hassanien R. (2018) Synthesis of Some Heterocyclic Compounds Derived from Indole as Antimicrobial Agents. Synth. Commun., 48 (4) 413–421.
(37) Sayed M., Younis O., Hassanien R., Ahmed M., Mohammed A. A. K., Kamal A. M., and Tsutsumi O. (2019) Design and synthesis of novel indole derivatives with aggregation-induced emission and antimicrobial Activity. J. Photochem. Photobiol. A., 383 (2019) 111969–111979.
(38) Kamal El Dean A. M., Zaki R. M., Geies A. A., Radwan S. M., and Tolba M. S. (2013) Synthesis and Antimicrobial Activity of New Heterocyclic Compounds Containing Thieno[3,2-c]Coumarin and Pyrazolo[4,3-c]Coumarin Frameworks. Russ. J. Bioorganic Chem., 39 (5) 553–564.
(39) Ahmed M., Younis O., Orabi E. A., Sayed A. M., Kamal El-Dean A. M., Hassanien R., Davis R. L., Tsutsumi O., and Tolba M. S. (2020) Synthesis of novel thienopyrimidines as biocompatible chromophores with aggregation-induced emission sensitive to molecular aggregation. ACS Omega, 5 (46) 29988-30000.
(40) Tolba M. S., Kamal El-Dean A. M., Ahmed M., Hassanien R., and Farouk M. (2017) Synthesis and Antimicrobial Activity of Some New Thienopyrimidine Derivatives. Arkivoc, 2017 (5) 229–243.
(41) Tolba M. S., Ahmed M., Kamal El-Dean A. M., Hassanien R., and Farouk M. (2018) Synthesis of new fused thienopyrimidines derivatives as anti-inflammatory agents. J. Heterocyclic Chem., 55 (2) 408–418.
(42) Younis O., Tolba M. S., Orabi E. A., Kamal A. M., Hassanien R., Tsutsumi O., and Ahmed M. (2020) Biologically-active heterocyclic molecules with aggregation-induced blue-shifted emission and efficient luminescence both in solution and solid states. J. Photochem. Photobiol. A., 400 (2020) 112642-112653.
(43) Tolba M. S., Kamal El-Dean A. M., Ahmed M., and Hassanien R. (2019) Synthesis, reactions, and biological study of some new thienopyrimidine derivatives as antimicrobial and antiInflammatory agents. J. Chin. Chem. Soc., 66 (5) 548–557.
(44) Hamed M. M., Kamal El-Dean A. M., Abdel-Mohsen Sh. A., and Tolba M. S. (2021) New Diclofenac Derivatives as Anti-Microbial, Anti-Inflammatory Agents: Design, Synthesis, Biological Screening, and Molecular Docking Study. Russ. J. Bioorganic Chem., 47 (1) 208-220.
(45) Abeed A. A. O., and Abdel Mohsen Sh. A. (2013) Synthesis, characterization and antimicrobial activity of new thiadiazoles, thiazolidines, and spiro (indole-azoles) linked to 2-pyrazolin-5-one. Eur. J. Sci. Res., 108 (2) 279-285.
(46) Bakhite E. A., Abeed A. A. O., and Ola E. A. Ahmed (2016) Synthesis and biological activity of some new fused thieno[2,3-b]pyridine derivatives; pyridothienopyrimidinones and pyridothienotriazinones. Assiut University Journal of Chemistry (AUJC), 45 (1) 47-57.
(47) Youssef M. S. K., Abeed A. A. O., and El Emary T. I. (2017) Synthesis and evaluation of chromene-based compounds containing pyrazole moiety as antimicrobial agents. Heterocycl commun., 23 (1) 55-64.
(48) Abeed A. A. O., Youssef M. S. K., and Rehab Hegazy R. (2017) Synthesis, anti-diabetic and renoprotective activity of some new benzazole, thiazolidin-4-one and azetidin-2-one derivatives. J. Braz. Chem. Soc., 28 (11) 2054-2063.
(49) Bakhite E. A., Abeed A. A. O., and Ahmed O. A. (2017) Fused thieno[2,3-b]pyridines: synthesis and characterization of new condensed pyridothienopyrimidines. Arkivoc, 2017 (4) 121-136.
(50) Youssef M. S. K., and Omar A. A. (2007) Synthesis and reactions of 5-amino-3-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-7-phenyl-7H-thiazolo[3,2-a]pyrimidine-6-carbonitrile. Monatsh. Chem., 138 (10) 989-995.
(51) Youssef M. S. K., Abbady M. S. A., Ahmed R. A., and Omar A. A. (2008) Reactions of 4-(2-aminothiazole-4-yl)-3-methyl-5-oxo-1-phenyl-2-pyrazo-line. Synthesis of thiazolo[3,2-a]pyrimidine and imidazo[2,1-b]thiazole derivatives. Monatsh. Chem., 139 (5) 553-559.
(52) O’Brien P. J., Abdel-Aal Y. A., Ottea J. A., and Graves J. B. (1992) Relationship of insecticide resistance to carboxylesterases in Aphis gossypii (Homoptera: Aphididae) from Midsouth cotton. J. Econ. Entomol., 85 651–657.
(53) Abbott W. S. (1925) A method of computing the effectiveness of an insecticide. J. Econ. Entomol., 18 265–267.
(54) Finney D. J. (1952) Probit Analysis: A Statistical Treatment of the Sigmoid Response Curve, 2nd Ed, Cambridge Univ. Press, Cambridge, U. K.