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Growing Science » Current Chemistry Letters » New approaches to the synthesis of diclofenac choline

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Current Chemistry Letters

ISSN 1927-730x (Online) - ISSN 1927-7296 (Print)
Quarterly Publication
Volume 6 Issue 4 pp. 159-166 , 2017

New approaches to the synthesis of diclofenac choline Pages 159-166 Right click to download the paper Download PDF

Authors: Elżbieta Dąbrowska-Maś, Wojciech Raś

DOI: 10.5267/j.ccl.2017.6.003

Keywords: Diclofenac choline, Anti-inflammatory agent, Oromucosal solution, Mouthwash solution

Abstract: The process described herein proceeds to obtaining diclofenac choline from choline bicarbonate and diclofenac acid in mild conditions, using non-toxic solvent, with the same impurity profile deriving from diclofenac particle as for diclofenac sodium EP. The substance is also substantially free from impurities deriving from choline and free from inorganic by-products, what means that the quality may be accepted for use as an active substance in medicine.

How to cite this paper
Dąbrowska-Maś, E & Raś, W. (2017). New approaches to the synthesis of diclofenac choline.Current Chemistry Letters, 6(4), 159-166.

Refrences

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Journal: Current Chemistry Letters | Year: 2017 | Volume: 6 | Issue: 4 | Views: 3351 | Reviews: 0

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