This work is devoted to development of optimum recipes of high-strength concretes based on filled binders with fine-milled anthropogenic mineral filler intended for earthquake resistant high-rise monolithic construction. The optimum recipes of concretes in this work have been developed on the basis of computations and experimental designing of cast concrete mixes with chemical additives and anthropogenic mineral fillers, as well as destructive inspection methods as the most precise for analysis of physicomechanical and deformation properties of concrete. The following raw materials have been used for production of high-strength concretes: natural quartz sands with the fineness modulus F.M. = 1.7-1.8; crushed limestone with the particles sizes of 5-20 mm; water reducing chemical additives and hardening retarder to control specifications of concrete mixes; plain Portland cement, grade PTs 500 D0; anthropogenic mineral additives (fillers) in the form of crushed concrete and ceramic bricks. Optimum recipes of monolithic concretes have been designed using anthropogenic raw materials including normal concrete grades with compressive strength of M30-M40 and high-strength concrete grades of M50-M80, characterized by high homogeneity of cement stone with significantly finer pores and lower shrinkage. Herewith, it has been established that fine-milled anthropogenic mineral filler in the form of crushed concrete and ceramic bricks at the ratio of 70:30, respectively, efficiently influences specifications of concrete mixes on their basis significantly increasing resistance of the mix against sedimentation and water gain. It has been established that the developed high-strength concretes based on filled binders with fine-milled anthropogenic mineral filler are characterized by high freeze–thaw resistance (from F400 to F600) and water tightness (W14 and higher), which is a solid base providing high lifecycle of such concretes.