The objective of this article is to assess the impact of supply chain relationship quality on supply chain performance and financial performance through environment uncertainty of high-tech agricultural enterprises in Vietnam. The study conducted data analysis based on 198 agricultural firms applying high technology in high-tech agricultural group and in all of Vietnam. The results show that, agricultural enterprises applying high technology with supply chain relationship quality had a strong positive impact on supply chain performance and supply chain flexibility. In addition, supply chain performance played a significant role in financial performance. Finally, Environment uncertainty and technological innovation played a statistically significant moderate role in the relationship between supply chain relationship quality and supply chain performance. For businesses with less environment uncertainty, the relationship was stronger and vice versa. The bigger the technology innovation, the stronger there the relationship.