Lots of work has been conducted to explore and explain inter-organizational relations between supply chain partners. However, we have noticed that there is no accurate agreement between authors. Therefore, to better understand this disparity, the authors have studied supply chain inter-organizational relationship dynamics in different industries to bring out an analytical framework that allows a better understanding of such an issue. Further, the framework is subjected to expert’s opinion and ranked using the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) approach. These case studies instruct professionals and researchers so that they bring up their level of abstraction that remains appropriate to catch this dynamic in order to guide decision-making and future research and studies.