The importance of information in achieving different organizational goals cannot be overstated since it ensures the rapid distribution of resources required to achieve desirable goals. The banking industry’s environment is incredibly dynamic and undergoes quick changes because of creativity, innovation, technological advancements, altered perceptions, and customer expectations. The center of the change curve is information and communication technology (ICT). Business organizations, particularly those in the banking sector, operate in a complex and competitive environment defined by shifting conditions and a volatile economic climate. Data for 20 MENA countries has been collected from the World Bank database between 1997 and 2021. Two-step System (Generalized Method of Moments) GMM were used to evaluate the influence of intrinsic features of individuals in a panel data set and avoid bias caused by omitted variables. The impact of the relationship between banks' performance and their use of ICT was evaluated in this study. The data analysis revealed that the impact of ICT on bank performance in MENA is positive. This suggests that a little shift in the banking industry's investment and adoption of ICT will result in a corresponding rise in profit levels.