Unlimited global competition for manufacturing companies means that companies must be efficient and effective, so implementing information technology is needed to produce fast and precise decisions. Manufacturing companies in East Java were obtained with a sample size of 89 companies as research respondents and processed using smart PLS. The research results show that the implementation of continuously adjusted information technology can provide improvements in supply chain integration, supply chain flexibility, and competitive advantage. Connections with external partners and transactions using information technology make it easier to coordinate internally and externally in decision making. Supply chain integration, which is described as collaborating with partners and involving them in decision making, can increase supply chain flexibility and competitive advantage. Manufacturing companies can increase flexibility in processes and develop new products, increasing market share and customer satisfaction compared to competitors. The company's supply chain flexibility can increase its competitive advantage. This research provides a practical contribution to company management in appropriately managing business strategy and in line with external changes. For operational practitioners, it includes enlightenment in maintaining the role and function of up-to-date information technology to make decision making easier. The theoretical contribution of the research is to enrich the theory's resources-based view on competitive advantage and operational system integration.