Economic growth is mostly dependent on small and medium-sized businesses (SMEs), especially in Bamenda III and similar districts. Examining how an entrepreneurial mindset affects the success of small and medium-sized enterprises (SMEs) in Bamenda III was the primary goal of this research. The study implemented a structured questionnaire and analyzed based on both descriptive and inferential statistics. Results from the ordinary least squares revealed that proactiveness behavior exerted a positive significant effect on SMEs_Performance in Bamenda III. Similarly, risk taking had a coefficient of 0.788, indicating a positive relationship with SMEs_Performance. Competitive aggressiveness had a positive coefficient indicating a positive association with SMEs_Performance, although it was not statistically significant at the conventional significance level. Innovativeness behavior had a positive statistically significant effect on SMEs_Performance. From a policy perspective, enhancing the entrepreneurial skills and mindset of SME owners and employees can foster a greater entrepreneurial orientation, leading to improved business performance.