Caring for cancer patients may create several negative emotions for their family members. Therefore, reducing or alleviating negative feelings are essential in improving mental and physical health of cancer patients’ family members. This research aims to identify the priority levels of the strategies used by cancer patients’ family members to cope with negative emotions, utilizing Analytic Hierarchy. Next, the proposed model is applied in the cases of Vietnamese cancer patients’ family members. Four groups of coping strategies against negative emotions of cancer patients’ family members are used in the model, including: (1) positive emotion-focused coping strategies; (2) negative emotion-focused coping strategies; (3) positive action-focused coping strategies; (4) negative action-focused coping strategies.