Digital transformation has a considerable impact on state institutions, forcing organizations and professionals to adapt to technological advancements. The objective of this study was to analyze the relationship between digital transformation and the job performance of employees at a hospital in the Junín region of Peru. The research is basic in nature and was developed using a quantitative approach with a correlational level. The population consisted of 552 administrative workers, and data was obtained from a sample of 227 employees who perform administrative activities within the hospital. Data analysis included descriptive statistics and the use of structural equation modeling with PLS -SEM estimation, employing SmartPLS 4.0 software. The results showed a positive and significant relationship between digital transformation and job performance. The dimensions of people, technology, processes, and quality showed significant effects on job performance, with statistically significant values (p < 0.05), confirming the robustness of the proposed structural model and its adequate fit. It is concluded that digital transformation significantly influences the job performance of administrative workers in the healthcare sector, contributing to process optimization, the strengthening of job skills, and improved organizational productivity. These findings highlight the importance of promoting comprehensive digital transformation strategies focused on human capital development and institutional efficiency.