Global supply chains are navigating ever more volatile and rapidly evolving conditions driven by technological innovation, geopolitical risks, environmental challenges, and changing customer requirements. Hence, conventional methods that focus on efficiency and cost reduction along the supply chain are not enough to stay competitive. In this context, an important strategic capability has emerged – the ability to be flexible, innovative, and adaptable, as well as efficient, standardised, and cost effective: supply chain ambidexterity. Notably, the extant literature on the relationship between SC ambidexterity and organizational performance have been scattered and segmented in various theoretical and operational viewpoints. To sum up previous research published between 2015 and 2025, this study used Systematic Literature Review (SLR) based on the PRISMA 2020 framework. A total of 34 peer-reviewed journal articles were included after screening and eligibility process both from Scopus and Web of Science database. The results reveal that supply chain ambidexterity has matured from a trade-off between exploration and exploitation, to a broader dynamic capability that is complemented by digital integration, resilience, analytics capability and organizational learning. Five key themes were found: conceptual foundations, lean–agile integration, digital technology enablement, performance outcomes, and environmental uncertainty. Organizations that are able to effectively blend efficiency with flexibility appear to have experienced an overall positive impact on their operational performance, innovation, responsiveness, resilience, and competitive advantage, according to the studies. Furthermore, some research gaps have been identified during the review, and future research recommendations are provided that could contribute to further research on the link between SC ambidexterity and OR performance.
