The nature and complexity of today’s supply chains have predisposed them to various risks, which are described under different terms, including disturbances, uncertainties and riots. Under these conditions, organizations are required to manage their supply chain in a way that is responsive to changes. The purpose of this study is to analyze the relationships between the strategies of coping with disturbances in supply chain networks. This is an applied research and using the research literature, 41 factors are selected for the solutions of coping with risk in supply chain networks. Then, these factors are entered in a questionnaire and presented for some supply chain experts. After that, Interpretative Structural Modeling (ISM) and Fuzzy MICMAC are implemented to rate the solutions of coping with risk in supply chain networks. The results show that the establishment of a supply chain continuity system at the seventh level is the basis of agility in the supply chain. The proper and efficient design of processes in the supply chain network will lead to proper operation in management solutions and appropriate synchronization in the supply chain networks. Using appropriate management solutions in synchronization leads to the integration and proper sharing of information within a supply chain network and between various supply chains and government. Additionally, using the synchrony and integration of supply chain networks, it is possible to design the proper supply chain network and appropriate communication between employees and network elements.