SMEs as a type of business have a high dependence on their owners and it is important for their owners to have entrepreneurial resilience and supply chain resilience. The main objective of this study is to determine the effect of entrepreneurial resilience and supply chain resilience on SMEs performance. The data were collected via a survey to 286 SMEs owners in Indonesia, especially culinary, fashion and craft businesses. SEM-PLS was used for data analysis. As a result, with the presence of supply chain resilience as a mediator, it turns out that entrepreneurial resilience has a stronger influence on SMEs performance. This shows that supply chain resilience also deserves attention to be owned by SMEs owners to achieve SMEs performance. Entrepreneur resilience and supply chain resilience owned by SMEs owners make it easier for SMEs in Indonesia to face increasingly fierce competition, uncertain business conditions to get optimal organizational performance.