The purpose of the current study was to investigate the determinants of small and medium manu-facturing enterprises’ export performance empirically in the context of Pakistan. The study adopted survey method to collect forty-five (45) responses from small and medium manufacturing firms through E-mail survey. The study produced four determinants of SME export performance, such as entrepreneurial orientation (EO), total quality management (TQM), business network (BN) and export market orientation (EMO). Thus, internal consistency reliability and discriminant validity were examined of the study instruments through panel expert’s opinion and the small sample size was investigated using statistical software SPSS-21 and smartPLS-3. The results of the study con-firmed that scale reliability and validity and moreover, current study found a positive relationship between TQM and SME export performance. On the other hand, the study also found insignificant relationship between EO, BN, EMO and SME export performance. Furthermore, the study recommended future study should validate the current study research framework on large sample size.