By advances in information technology and considering the fast pace of innovation in targeted technologies, blended learning with the aim of satisfying the needs of blended learning is composed of online learning and face-to-face learning. The aim of the present paper is to study the impact of blended learning on the relevant factors through a mixed method. The study is considered fundamental in terms of research methodology. The present paper is carried out on students of West Tehran Payame Noor University, Iran through a questionnaire. According to the results, it is concluded from the perspective of students that although blended learning is formed of several factors such as face-to-face learning and virtual learning, this type of learning has significant impact on its constituent elements as well as on relevant factors related to this type of learning. Finally, the effectiveness of blended learning, virtual and face-to-face learning in accordance on their factors were determined and assessed which ultimately led to conclusions and recommendations to advance research objectives.